Article: Modulation of BK channels contributes to activity-dependent increase of excitability through MTORC1 activity in CA1 pyramidal cells of mouse hippocampus.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Springer SJ; Burkett BJ; Schrader LA Front Cell Neurosci, 2014
Spike amp (mV) | AHP amp (mV) | Threshold (mV) | Input resistance (MΩ) | Spike number | Sag (mV) | Animal # | |
---|---|---|---|---|---|---|---|
Control | 95.2 ± 1.7 | -7.9 ± 0.8 | -47.3 ± 0.9 | 200 ± 27.8 | 11.8 ± 1.1 | 1.9 ± 0.2 | 18 |
Paxilline | 93.1 ± 1.9* | -6.9 ± 0.6 | -50.3 ± 0.9**** | 212 ± 26.6 | 14.8 ± 1.2**** | 2.3 ± 0.2 | |
Control | 85.3 ± 7.5 | -6.6 ± 1.4 | -49.8 ± 1.6 | 197.6 ± 16.8 | 14.0 ± 3.2 | 2.1 ± 0.6 | 5 |
iberiotoxin | 85.8 ± 4.7 | -6.7 ± 1.4 | -51.6 ± 1.2 | 239.0 ± 27.0 | 22.2 ± 2.8* | 2.0 ± 0.8 | |
Control | 93.2 ± 1.3 | -6.8 ± 0.6 | -48.5 ± 1.1 | 183.8 ± 10.8 | 15 ± 2.1 | 1.5 ± 0.2 | 13 |
TBS | 90.3 ± 1.3** | -5.7 ± 1.0 | -50.0 ± 1.3 | 205.5 ± 15.2** | 19 ± 2.1*** | 1.5 ± 0.2 | |
TBS | 95.0 ± 2.3 | -8.2 ± 0.5 | -49.0 ± 1.0 | 230.0 ± 32.4 | 15.2 ± 2.6 | 3.2 ± 0.5 | 9 |
TBS + Pax | 93.5 ± 2.4 | -8.2 ± 0.8 | -49.8 ± 1.3 | 243.3 ± 38.0 | 15.6 ± 1.7 | 3.3 ± 0.6 | |
Control | 95.0 ± 1.5 | -10.3 ± 1.0 | -46.1 ± 1.3 | 180.0 ± 12.6 | 12.3 ± 2.1 | 2.4 ± 0.2 | 6 |
Rapamycin | 91.5 ± 2.5 | -7.4 ± 0.9*** | -49.7 ± 1.1** | 186.8 ± 11.6 | 15.5 ± 2.6** | 2.4 ± 0.3 | |
TBS+Pax | 98.7 ± 2.1 | -9.8 ± 1.0 | -48.5 ± 1.0 | 227.3 ± 24 | 17.2 ± 3.5 | 3.4 ± 0.5 | 12 |
TBS+Pax + Rap | 96.4 ± 1.8 | -8.6 ± 1.4 | -49.7 ± 1.8 | 233.3 ± 27.0 | 20.1 ± 3.9* | 3.1 ± 0.5 |